Ajab Bhanje Ki Gazab Maamiyan follows 22-year-old Raj, who moves in with his uncle Surendra after finishing his studies, hoping to find a job. There, he meets Kanchan, Surendras unfulfilled and childless wife. One unexpected encounter brings them intimately close. Seeing a new spark in her life, Kanchan introduces Raj to her two other mamis — Anita and Madhu. This marks the start of Rajs wild, funny, and unexpected journey.